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Adjunctive Rifampicin to Reduce Early mortality from STaphylococcus aureus bacteraemia: a multi-centre, randomised, blinded, placebo controlled trial
Will taking rifampicin as an extra antibiotic help sick people with S. aureus blood infections?
What is this study about?

Staphylococcus aureus (or S. aureus) is a bug which can cause serious infections, including infections of the blood. Doctors use an antibiotic to cure S. aureus but sometimes the infection comes back and sometimes the antibiotic does not succeed.

We want to find out whether or not giving an extra antibiotic, called rifampicin, in addition to the standard antibiotic treatment, will help sick people with S. aureus blood infections.

Who is included?

To join ARREST participants will be in hospital and have a blood infection which the doctor thinks is caused by S. aureus.

Contact details

When is it taking place?

ARREST opened to recruitment in November 2012. Participants are followed up for 12 weeks. It is anticipated the trial will be completed in approximately 4 years.

Where is it taking place?

ARREST is taking place in hospitals in the UK.

Who is funding the study?

It is funded by the NIHR Health Technology Assessment (HTA) programme, UK.

Further information

Type of study:
Randomised trial
Open to recruitment
Study start date:
26 November 2012

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