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The HIV Paediatric Prognostic Markers Collaborative Study (HPPMCS) is a collaboration between investigators of European and US cohort studies and randomised trials of ART or immune therapies in perinatally HIV-1 infected children.

The following studies participate in the HIV Paediatric Prognostic Markers Collaborative Study (HPPMCS):

The study is coordinated by the MRC Clinical Trials Unit, UK. If you have any comments on these web pages please contact Trinh Duong (td@ctu.mrc.ac.uk).

Steering Commitee

AG Babiker, M Bulterys, DT Dunn, T Duong, C Gabiano, L Galli, C Giaquinto, DM Gibb, L Gray, DR Harris, M Hughes, R McKinney, L Mofenson, J Moye, ML Newell, S Pahwa, P Palumbo, C Rudin, M Schluchter, M Sharland, W Shearer, B Thompson, P Tookey.

Clinical centres:

Collaborative HIV Paediatric Study (CHIPS) of UK and Ireland

This is a collaboration between the National Study of HIV in Pregnancy and Childhood (NSHPC) at the Institute of Child Health, London and the Medical Research Council’s Clinical Trials Unit (MRC CTU), London. National surveillance of paediatric HIV in the UK and Ireland is undertaken by the NSHPC in collaboration with the Health Protection Agency Centre for Infections, Health Protection Scotland, the British Paediatric Surveillance Unit of the Royal College of Paediatrics and Child Health, and the Royal College of Obstetricians and Gynaecologists. The NSHPC receives support from the Health Protection Agency and the Medical Research Council. The majority of HIV infected children are followed up at the 17 British and Irish centres participating in the Paediatric European Network for Treatment of AIDS (PENTA), co-ordinated through the Medical Research Council’s Clinical Trials Unit. CHIPS receives additional support from these centres, which include: Our Lady’s Hospital for Sick Children, Dublin (K Butler, E Hayes, R Griffin); City Hospital, Edinburgh (J Mok); Edinburgh Royal Hospital for Sick Children (J Mok); Ninewells Hospital, Dundee (J Petrie); St Mary’s Hospital, London (J Evans, G Tudor-Williams, J White, S Head); Great Ormond St Hospital for Children NHS Trust, London (D Gibb, V Novelli, B Ohene-Kena, M Clapson); St George’s Hospital, London (M Sharland, S Donaghy); Ealing Hospital, London (K Sloper); Heartlands Hospital, Birmingham (S Rose, A Riordan); The Children’s Hospital, Sheffield (A Finn, F Shackley, J Hobbs); John Radcliffe Hospital, Oxford (C Richards, P Heath, S Segal); St Thomas; Hospital, London (G du Mont R Cross); King’s College Hospital, London (C Ball, D Graham, A Waters); Chelsea and Westminster Hospital, London (H Lyall, P Seery); Newham General Hospital, London (E Cooper, S Wong, T Fisher); Royal Free Hospital, London (V Van Someren, S McKenna); Lewisham Hospital, London (J Stroobant); Royal Hospital for Children, Bristol (A Foot).

European Collaborative Study

C Giaquinto, O Rampon, V Giacomet, A De Rossi (Universita degli Studi di Padova, Italy); I Grosch-Wörner (Charite Virchow-Klinikum, Berlin, Germany); J Mok (Royal Hospital for Sick Children, Edinburgh); I Bates, I de José, F Hawkins, MC Garcia-Rodriguez, C Ladrón de Guevara, J Ma Peña, J Gonzalez Garcia, JR Arribas Lopez (Hospital Infantil La Paz, Madrid); F Asensi-Botet, MC Otero, D Pérez-Tamarit, A. Orti, M.J San Miguel, R de la Torre (Hospital La Fe, Valencia, Spain); H Scherpbier, M Kreyenbroek, K Boer (Academisch Medisch Centrum, Amsterdam, The Netherlands); AB Bohlin, E Belfrage, L Navér, (Huddinge and Karolinska University Hospitals, Sweden); J Levy, M Hainaut, A Peltier, S Wibaut, P Barlow, (Hospital St Pierre, Brussels, Belgium); A Ferrazin, D Bassetti, (Department of Infectious Diseases, University of Genoa, Italy); A De Maria (Department of Internal Medicine, University of Genoa, Italy), C Gotta (Department of Obstetrics and Gynecology--Neonatology Unit, University of Genoa, Italy); A Mûr, A Payà, M Viñolas, MA López-Vilchez, M Rovira, R Carreras, E Esteban Tores, S Herrero Perez (Hospital del Mar, Universidad Autonoma, Barcelona, Spain); and N H Valerius (Hvidovre Hospital, Denmark).
The European Collaborative Study is a concerted action of the European Commission (Biomed II PL 97 2005 and QLRT-1999-30002). The Medical Research Council (UK) provides support to the coordinating centre.


Italian Register for HIV Infection in Children

The following persons and Institutions constitute the “Italian Register for HIV infection in children”.
Azienda Ospedaliera “G. Salesi”, Ancona: Patrizia Osimani. Dipartimento Biomedica, Università degli Studi di Bari: Domenico De Mattia and Mariano Manzionna. Azienda Ospedaliera di Venere e Giovanni XXIII, Bari: Cesare Di Bari. Ospedali Riuniti di Bergamo: Maurizio Ruggeri and Nicoletta Pellegrini. Clinica Pediatrica III, Università di Bologna: Massimo Masi. Ospedale Maggiore C.A. Pizzardi, Bologna: Matilde Ciccia. Istituto Clinica Pediatrica, Università di Bologna: Marcello Lanari and Valentina Venturi. Divisione Pediatrica, ASL 23 Imola, Bologna: Francesco Baldi. Azienda Ospedaliera A. Di Summa, Brindisi: Piergiorgio Chiriacò. Clinica Pediatrica, Spedali Civili-Università di Brescia: Richard-Fabian Schumacher, Marzia Duse, and Mara Castagna. II Clinica Pediatrica, Università di Cagliari: Carlo Dessì. Istituto di Clinica Pediatrica, Università di Cagliari: Maurizio Dedoni. Patologia Neonatale, Università di Cagliari: Roberto Cavallini, Donatella Gariel. Neonatologia e terapia intensiva, Università di Chieti: Giuseppe Sabatino. Divisione Pediatria, Az. Ospedaliera S.Croce e Carle, Cuneo: Giulia Pomero. Divisione Pediatria, Ospedale S. Anna, Como: Maurizio Sticca. Cattedra di Pediatria, Università di Catanzaro: Elisa Anastasio. Clinica Pediatrica, Università di Ferrara: Maria Teresa Bezzi. U.O.A. Malattie Infettive, Università di Firenze: Paola Gervaso, Elena Chiappini, and Stefania Paganelli. Divisione Pediatrica, Ospedale Infermi, Rimini: Maria Teresa Cecchi. I Clinica Malattie Infettive, Istituto Giannina Gaslini, Genova: Dante Bassetti and Raffaella Rosso. Divisione di Pediatria, E.O. Ospedali Galliera, Genova: Danilo Cosso and Marida Bartolini. Divisione Malattie Infettive, Istituto Giannina Gaslini, Anna Timitilli. Reparto di Neonatologia, Ospedale S. Martino, Genova: Cristina Gotta. Divisione Pediatrica, Ospedale Civile di Imperia: Carlo Amoretti. Clinica Pediatrica 1, Università di Milano: Raffaella Pinzani, Jelena Bojanin. Cattedra di Clinica Pediatrica IV, Università di Milano: Alessandra Viganò, Vania Giacomet, and Laura Schneider. Clinica Pediatrica V, Università di Milano: Vincenzo Zuccotti, Enrica Riva, and Marcello Giovannini. Centro Materno Infantile, Clinica Mangiagalli, Milano: Gabriele Ferraris. Div. di Pediatria “Mariani”, Ospedale Niguarda-Cà Granda, Milano: Rita Lipreri and Chiara Moretti. Divisione di Pediatria, Az. Ospedaliera Carlo Poma, Mantova: Mauro Stronati. Clinica Pediatrica, Policlinico, Modena: Monica Cellini and Maria del Carmen Cano. Pat. Neonatale e Terapia Intensiva, Università Federico II di Napoli: Filippo Ciccimarra and Wilma Buffolano. Dipartimento di Pediatria, Università Federico II di Napoli: Alfredo Guarino and Eugenia Bruzzese. Prima Divisione di Pediatria, Ospedale della SS. Annunziata, Napoli: Luigi Tarallo. Ospedale Casa del Sole, Palermo: Adriana Sanfilippo. Istituto di patologia Infettiva, Ospedale Bambini, Palermo: Amelia Romano. Dipartimento di Pediatria, Università di Padova: Osvalda Rampon, Ruggiero D’Elia, and Ezia Ruga. Istituto di Clinica Pediatrica, Università di Pisa: Rita Consolini, Annalisa Legitimo. Divisione Pediatria Sez. Infettivi, Az. Ospedaliera di Parma: Igilio Dodi, Angelica Barone. Clinica Pediatrica, Università di Pavia: Anna Maccabruni, Alessandra Moretti, and Giuseppe Michelone. Div. di Pediatria, Az. Osp. S. Maria Nuova, Reggio nell’Emilia: Cristiana Magnani. I Clinica Pediatrica, Università “La Sapienza”, Roma: Paola Falconieri. Istituto Clinica Pediatrica, U.C.S.C. Policlinico A. Gemelli, Roma: Carlo Fundarò, Orazio Genovese, and Stefania Salvucci. Istituto Puericultura, Università “La Sapienza”, Roma: Anna Maria Casadei. Ospedale Bambino Gesù, Roma: Guido Castelli Gattinara, Stefania Bernardi, and Paolo Palma. Reparto Malattie Infettive Infanzia, I.R.C.C.S. L. Spallanzani, Roma: Gianfranco Anzidei, Stefano Cerilli, and Rosa Chiodi. Dipartimento Malattie Infettive Tropicali, Università La Sapienza, Roma: Salvatore Catania. Divisione Pediatria Infettivi, Sassari: Antonella Ganau. Divisione Malattie Infettive, Ospedale SS. Annunziata, Taranto: Letizia Cristiano. I U.O. di Pediatria, Ospedale S. Chiara di Trento: Antonio Mazza and Benito Rambaldi. Dipartimento di Scienze Pediatriche, Università di Torino: Sara Garetto, Carlo Scolfaro, and Elvia Palomba. Divisione Malattie Infettive, Az. Osp. S.Antonio Abate, Trapani: Vincenzo Portelli. Clinica Pediatrica, Istituto per l’Infanzia “Burlo Garofalo”, Trieste: Marco Rabusin. Divisione Pediatria, Az. Ospedaliera Busto Arsizio, Varese: Antonio Pellegatta. Divisione di Pediatria, Ospedale Civile Maggiore, Verona: Maitè Molesini.


NICHD Intravenous Immunoglobulin Study Group

Lincoln Hospital Center, Bronx, NY: Kiran Shah MD and Jean Chow MD. Cornell Medical Center, New York City, NY: Paul Edelson MD and Deborah Sanders MD. Schneider Children's Hospital, Queens, NY: Vincent Bonagura MD and David Valacer MD. Beth Israel Medical Center, New York City, NY: Walter Hensley MD. Metropolitan Medical Center, New York City, NY: Mahrukh Bamji MD. New York Medical College, Valhalla, NY: Asha Gupta MD and Karl I. Li MD. Harlem Hospital Center, New York City, NY: Elaine J. Abrams MD. State University of New York Health Science Center, Brooklyn, NY: Senih Fikrig MD. Saint Luke's/Roosevelt Hospital Center, New York City, NY: Saroj S. Bakshi MD. North Shore University Hospital, Manhasset, NY: Savita Pahwa MD. New York University Medical Center-Bellevue Hospital, New York City, NY: Keith Krasinski MD. Columbia Babies Hospital, New York City, NY: Jane Pitt MD. Albert Einstein College of Medicine, Bronx, NY: Larry Bernstein MD and Ayre Rubinstein MD. University of Connecticut Health Center, Hartford, CT: George Johnson MD. Boston City Hospital, Boston, MA: Ellen R. Cooper MD. University of Medicine and Dentistry of New Jersey-Robert Wood Johnson Medical School, New Brunswick, NJ: Lawrence Frenkel MD. Saint Christopher's Hospital for Children, Philadelphia, PA: Harold W. Lischner MD and Stephen A. Raphael MD. University of Maryland, Baltimore, MD: John P. Johnson MD. Children's Hospital National Medical Center, Washington DC: Tamara Rakusan MD. Emory University School of Medicine, Atlanta, GA: Steven Nesheim MD, Andre Nahmias MD, and Harry Keyserling MD. The Children's Memorial Hospital, Chicago, IL: Ram Yogev MD and Ellen Chadwick MD. University of Illinois Chicago College of Medicine, Chicago, IL: Kenneth Rich MD. Texas Children's Hospital, Houston, TX: I. Celine Hanson MD and William. Shearer MD PhD. Children's Hospital Medical Center, Oakland, CA: Ann Petru MD. University of Puerto Rico, San Juan, Puerto Rico: Clemente Diaz MD and Luis Colon Santini MD. San Juan City Hospital, San Juan, Puerto Rico: Eleanore Jimenez MD. Ramon Ruiz Arnau University Hospital, Bayamon, Puerto Rico: David Garcia-Trias MD and Carmen Acantilado MD.


Perinatal AIDS Collaborative Transmission Study

Bronx Lebanon Hospital: Saroj Bakshi, Murli Purswani, Emma Stuard; Centers for Disease Control and Prevention: Marc Bulterys, April Bell, Mary Glenn Fowler, Darcy Freedman, Linda Koenig, RJ Simonds, Jeffrey Wiener; Emory University School of Medicine: Steve Nesheim, Andre Nahmias, Mary Sawyer, Michael Lindsey; Harlem Hospital Center: Elaine Abrams, Louise Kuhn, Susan Champion, Julia Floyd, Cynthia Freeland, Pamela Prince; Jacobi Hospital Center: Jacobo Abadi, Joanna Dobroszycki, Adell Harris, Genevieve Lambert; Metropolitan Hospital Center: Mahrukh Bamji, Lynn Jackson; Medical and Health Research Association of New York City, Inc: Rosalind Carter, Tina Alford, Mary Ann Chiasson, Donald Thea, Jeremy Weedon; Montefiore Medical Center: Marguerite Mayers, Marcella Naccarato, Valerie Nedwin, Ellie Schoenbaum; University of Medicine and Dentistry of New Jersey: Paul Palumbo, Arlene Bardeguez, Linda Bettica, Thomas Denny, James Oleske. University of Maryland School of Medicine: Peter Vink, Lindsey Alger, John Farley, Vicki Tepper, Prasanna Nair, Susan Hines.


Pediatric AIDS Clinical Trials Group (PACTG)

Agence Nationale de Recherche sur le SIDA Protocol 024 Study Group, Paris: Blanche S, Mandelbrot L, Rouzioux C; Albert Einstein College of Medicine, New York: Bernstein LJ, Landor M, Rubinstein A, Shliozberg J, Youchah J; Baltimore Pediatric ACTG: Flautt L, Livingston R, Vink P; Baylor University, Houston: Doyle M, Hanson CG, Kline MW, Laflen J, Shearer WT, Rayborn T; Baystate Medical Center Springfield, Mass: Stechenberg BW, Sullivan JL; Bellevue Hospital Center/NYU, New York: Allen M, Borkowsky W, Chandwani S, Deygoo N, Kaul A, Lawrence R, Mintor M, Rigaud M, Zuckerman C; Beth Israel Hospital, Boston: McIntosh K, Sachs B, Tuomala R; Boston City Hospital, Boston: Cooper ER, Damon B, Donegan P, Pelton SI, Regan AM; Bronx Lebanon Hospital Center, New York: Barnett T, Biernick W, Cihak P, Dobrosyzcki J, Nozyce M, Solomon L, Steiner A, Wiznia A, Young B; Case Western Reserve University Cleveland: Chance M, Zucker M, Toltzis P; Children’s Hospital and Medical Center, Seattle: Burchett SK, Carpenter J, McLellan C, Watts DH; Children’s Hospital at Albany Medical Center, Albany NY: Lepow M, Samelson R, Wade N; Children’s Hospital Oakland: Petru, A; Children’s Hospital of Boston: Al-Attar I, Burchett SK, Jacobs D, Karthas N, Knox-Burke K, Rubin-Hale A; Children’s Hospital of Boston, Brigham and Women’s Hospital: McIntosh K, Ruomala R, Sachs B; Children’s Hospital of Michigan, Wayne State University, Detroit: Cromer C, Harrison DD, Jones TB, Moore E; Children’s Hospital of New Jersey: Connor EM, McSherry G, Oleske J; Children’s Hospital of New Jersey /St Joseph’s Hospital and Medical Center: Hutcheon N; Children’s Hospital of New Jersey/ University of Medicine and Dentistry of New Jersey: Colabelli NB; Children’s Hospital of Philadelphia: Maniglia C, Rudy B, Rutsetein R, Schaible D; Children’s Hospital of Philadelphia, Jefferson Medical College Philadelphia: Anday E, Friank I, Silverman N; Children’s Medical Center at Stony Brook, Sony Brook, NY: Baker D, Nachman S, Vomero A; Children’s Medical Center of Dallas: Ross DK, Squires J; Children’s Memorial Hospital Chicago: Chadwick E, Fonken D, Johnson D, Chadwick E, Klauke BJ, Silio M, Yogev R; Children’s National Medical Center, Washington DC: Ellaurie M, Herzog K, Hoppe J, Jones S, Rakusan T, Sever J, Zamer S; Cinncinnati Children’s Hospital, Cincinnati: Baker RC, Siegel R; Columbia Presbyterian Medical Center: Clark P, Drucker L, Gershon A, Kanem N, Pitt J, Shea K; Columbia University, New York: Fox H, Gershon A, Kanem N, Pitt J; Columbus Children’s Hospital / Ohio State University, Columbus: Callaway C, Crim LB, Hunkler J, Brady MT, Koranyi K; Cooper Hospital: Mintz M; Cornell Medical Center, New York: Cervia J, Edelson PJ, Hinds GA, LaGuardia KD, Sanders-Laufer D, Schauer CM;Duke University Medical Center, Durham NC: Hurwitz J, Valentine M, Wilfert C, Donnelly M, Lane BA, Livingston E, McKinney R, Santacroce S; Emory University, Atlanta: Keyserling HL, Meadows L, Nahmias AJ, Nesheim SR, Sarver JC, Sawyer MK; Harlem Hospital Center, New York: Abrams E, Brinney J, Calo D, Champion S, Frere M, Kanem N, Urbano R; Hemophilia Center of Western Pennsylvania: Carfagna E, Miller B, Ragni MV; Hoffmann-LaRoche, Inc: Dennin R, Lim A, Ward A; Howard University, Washington, DC: Finke H, Jayam-Trouth A, Wilson S, Kamara A, Rana S, Smith D; John Hopkins University, Baltimore: Livingston R, Hutton N, Modlin H, Vink P, Yolken R; Kings County Hospital Center: Bergin HF, Difilippo G, Handlesman E, Mendez H, Winthrop HF; Lincoln Hospital Center: Clintron AA, Rao S, Shah K, Villaricia NC; Los Angeles County, University of Southern California Medical Center: Khoury M, Kjos S, Kovacs A, Ono J; Medical University of South Carolina, Charleston: Connelly GM, Johnson GM, Newman RB, Turner, RB; Metropolitan Hospital Center, New York: Bamji M, Dummitt M, Inandar S, Kennedy G, Novita K, Stumpf-Koster D; Milton S. Hershey Medical Center, Hershey PA: Cubble LJ, Eyster ME, Dossett J; Mt. Sinai Medical Center, New York: Barzelai A, Butler L, Chusid E, Heaton S, Hodes D, Piwoz J, Rhone L, Sacks HS, Warford R; New Jersey Medical School, Newark: Bardeguez A, Colabelli N, McSherry G, Oleske J, Picardi J; New York Medical College, Westchester Hospital, Valhalla: Ahern L, Gupta A, Kirshenbaum N, Li K, Munoz J; North Shore University Hospital: Baksji S, Matias A, Pahwa S, Tagupa Z; Northwestern University School of Medicine, Children’s Memorial Hospital, Chicago: Garcia P, Stanislawski D, Yogev R; Ohio State University, Columbus: Crim LB; Ramon Ruiz Arman University Hospital, Bayamon, Puerto Rico: Aguayo R, Bayron V, Diaz L, Garcia-Trias DE, Reyes EJ; Rhode Island Hospital, Women and Infants Hospital, Brown University, Providence: Carpenter M, Flynn C, Kneut C, Smith P, Sweeney PJ; Robert Wood Johnson Medical School: Gaur S, Williams PW; San Juan City Hospital, San Juan, Puerto Rico: Abreu E, Berrios Z, Carrer MT, Cordero A, Gonzales M, Jimenez E, Perez L; Schneider Children’s Hospital, New Hyde Park NY: Bonagura V, Colter C, Rosenthal R, Schuval SJ, Valacer DJ; St Luke’s – Roosevelt Hospital, New York: Bakshi S, Grieco MH, McKinley G, Rivera J, Rivers GJ; St. Christopher’s Hospital for Children: Gregonis SW, Kamrin AL, Lischner HW, Raphael SA, Treston CS; St. Jude’s Children’s Research Hospital, Regional Medical Center, Memphis, Tenn: Flynn PM, Hughes W, Lancaster D, Shenep L; State University of New York at Stony Brook: Davi M, Nachman S; State University of New York Health Science Center, Brooklyn: Fikrig S, Handelsmen E, Minkoff H, Moallom H, Schuller G, Wiltshire S; State University of New York Health Science Center, Syracuse: Contello K, Cunningham CD, Hagen JH, Kirkwood K, Weiner LB; Texas Children’s Hospital, Baylor College of Medicine, Houston: Doyle M, Hammill HA, Kline M; Tulane University, New Orleans: Alchediak T, Bienvenu S, Calligaro D, Pramberg J, Robinson WR, Silio M, Van Dyke RB; UCLA Medical Center, Los Angeles: Boyer PJJ, Bryson YJ, Church J, Deveikis A, Israele V A, Gillette S, Keller M, Krogstad P, Stiehm ER, Taylor S, Wong V; University of Alabama: Brien-Berkow P, Cooney MF, Jones L, Crain M, Hauth J; University of California, San Diego: Besser MJ, Caffery M, Dankner WM, Instone S, Spector SA, Stangl L; University of California, San Francisco: Landers DV, Manio EB, Trebithick D, Wara D, Williams-Herman D; University of California, San Francisco and Children’s Hospital Oakland: Dorenbaum A, Petru A; University of Cincinnati College of Medicine, Cincinnati: Baker R, McOwen N, Siddiqi TA, Skahan KJ, Siegel R; University of Colorado, Children’s Hospital, Denver: Levin MJ, McCarthy M, McFarland E, Salbenblatt C; University of Connecticut Health Science Center: Johnson GM, Robinson J, Simonik M, Wells L; University of Florida College of Medicine at Jacksonville: Eagle LM, Rathore M; University of Illinois at Chicago: Hayani K, Horn P, Rich K, Turpin D, Vajaranan M; University of Maryland, Baltimore: Lovelace S, Vink P, Houck D, Livingston R; University of Massachusetts, Worcester: Stechenberg BW, Cheeseman S, Luzuriaga K, Robinson J, Sullivan JL; University of Medicine and Dentistry of New Jersey: Bardeguez A, Frenkel L, Gaur S, Johnson RW, Kechula IM, McSherry G, Oleske J, Scudder RC; University of Miami: Gourley J, Halldorsdottir K, Mendoza C, Mitchell C, Scott GB; University of Minnesota, Minneapolis: Balfour HH, Goodroad BK, Jones CR; University of North Carolina Hospital at Chapel Hill: Dudek V, Katz V, Lim W, Mundorg L, Santucci S; University of Puerto Rico, San Juan: Beauchamp B, Diaz C, Flores L, Hyllier G, Lugo L, Rivera C, Zorrilla C; University of Rochester Medical Center, Rochester NY: Gigliotti F, Abramowicz JS, Frenkel L, Kassman BP, Lambert JS, Murante B; University of Rochester/ Children’s Hospital-Buffalo: Kelly C; University of Texas: Cantini M, Doyle M; University of Washington, Children’s Hospital and Medical Center, Seattle: Melvin A, Mohan K, Burchett SK, Corey L, Foster I; Washington University, St Louis: Breuklandr L, Royal M, Storch G; Westchester Hospital: Arlievsky N, Shand L, Yale University: Andiman WA, Romero SG.


Paediatric European Network for Treatment of AIDS (PENTA)

Belgium : Hôpital Saint-Pierre, Brussels (J Levy, A Alimenti, A. Peltier, M. Hainaut). Brazil : Instituto de Infectologia “Emilio Ribas” ; São Paolo (M Della Negra, W Queiroz). Canada: Canadian HIV Trials Network, Vancouver (D Zarowny, S Korasheh, S Cleary) ; Children’s Hospital, Vancouver (J Forbes); Alberta Children’s Hospital (T Jadavji); University of Alberta, Edmonton (W Vaudry). France : Centre Hospitalier Universitaire, Nantes (F Mechinaud); Hôpital Arnaud de Villeneuve, Montpellier (J Nicolas), Hôpital Necker-Enfants Malades, Paris (M Debré, F Veber) ; Hôpital Robert Debré, Paris (M. Lévine, A. Faye), Hôpital Jean Verdier, Bondy (E Lachassinne); Centre Intercommunal de Créteil, Créteil (S Lemerle); Centre Hospitalier Regional d’Orléans (J Donadieu, F Labbay) ; CHU de Nancy, Hôpital d’Enfants (P Bordigoni, AS Carret). Germany : Universitäts - Kinderklinik Düsseldorf (V Wahn, T Niehues); Universitäts - Kinderklinik, Hamburg (C Dammann, A Sobanjo); Universitäts - Kinderklinik, Munich (G Notheis, U Wintergerst); Cnopf’sche Kinderklinik, Nürnberg (B Heeren, B Hinkelmann, M Dehn); Kinderklinik – Ludwigshafen (H Rütschle); Charité Virchow Klinikum, Berlin (I Grosch-Wörner, K Seel). Ireland: Our Lady’s Hospital for Sick Children, Dublin (K Butler, E Hayes, R Griffin). Italy: Università di Padova (C Giaquinto, S Cozzani); Istituto per l’Infanzia “Burlo Garofolo”, Trieste (A De Manzini, C Salvatore); Ospedale S Chiara, Trento (A Mazza); Spedali Civili, Brescia (M Duse, A Soresina, Istituto G Gaslini); Genova (A Loy, E Pontali, F Fioredda); Università di Milano (A Plebani, R Pinzani); Ospedale Bambino Gesù, Rome (G Castelli-Gattinara, S Bernardi); Ospedale Niguarda, Milano (R Lipreri); Ospedale Civile, Modena (M Cellini, C Baraldi); Ospedale Infantile “Regina Margherita”, Torino (E Palomba, C Gabiano); IRCCS Policlinico San Matteo, Pavia (D Caselli, A Maccabruni); Università di Napoli “Federico II”, Naples (A Guarino, S Russo, A Castaldo); Ospedale “G Salesi”, Ancona (P Osimani, M Vignini); Ospedale S.Paolo, Milano (G Zuccotti); Ospedale dei Bambini, Palermo (V Portelli, B Alabastro). Netherlands: Academisch Ziekenhuis bij de Universiteit van Amsterdam (H Scherpbier, P Leeuwen). Portugal: Hospital Dona Estefania, Lisbon (L Rosado, MF Candeias). Spain: Hospital Civil de Basurto, Bilbao (A Delgado, J Aristegui); Hospital Materno-Infantil La Paz, Madrid (I De José Gomez, F. Baquero, M. Garcia Miguel) ; Hospital Nuestra Señora de Aranzazu, San Sebastian (J Echeverria Lecuona); Instituto de Salud Carlos III, Madrid (P Martin Fontelos, MJ Mellado Pena); Hospital Clinico Universitario Lozano Blesa, Zaragoza (C Baselga, J M Perez Gonzales, M Gracia Casanova); Hospital Virgen del Rocio, Sevilla (J A Leon Leal); Hospital Materno-Infantil 12 de Octubre, Madrid (J Ruiz Contreras, J T Ramos Amador, J Clemente Pollan); Hospital La Fe, Valencia (F Asensi Botet, C Canosa, D Perez Tamarit, M C Otero Reigada); Hospital del Mar, Barcelona (A Mur Sierra); Hospital General Gregorio Marañon, Madrid (MD Gurbindo Gutierrez, ML Navarro Gomez, T Hernandez); Samplelayo Hospital Son Dureta, Palma de Mallorca (L Ciria Calavia); Hospital Germans Trias i Pujol, Barcelona (C Rodrigo); Hospital San Juan de Dios, Barcelona (C Fortuny Guasch), Hospital Vall’Hebron, Barcelona (JM Bertran Sanges, L Garcia). Sweden: Huddinge Hospital (A Bohlin). Switzerland: Universitäts-Kinderklinik , Basel (C Rudin, D Rinaldi); Hôpital des Enfants, Geneva (CA Siegriest, CA Wyler, V Masserey) ; Universitäts-Kinderklinik, Zurich (D Nadal). UK: City Hospital, Edinburgh (J Mok); Edinburgh Royal Hospital for Sick Children (J Mok); Ninewells Hospital, Dundee (J Petrie); St Mary’s Hospital, London (J Evans, G Tudor-Williams, J White, S Head); Great Ormond St Hospital for Children NHS Trust, London (D Gibb, V Novelli, B Ohene-Kena, M Clapson); St George’s Hospital, London (M Sharland, S Donaghy); Ealing Hospital, London (K Sloper); Heartlands Hospital, Birmingham (S Rose, A Riordan); The Children’s Hospital, Sheffield (A Finn, F Shackley, J Hobbs); John Radcliffe Hospital, Oxford (C Richards, P Heath, S Segal); St Thomas; Hospital, London (G du Mont R Cross); King’s College Hospital, London (C Ball, D Graham, A Waters); Chelsea and Westminster Hospital, London (H Lyall, P Seery); Newham General Hospital, London (E Cooper, S Wong, T Fisher); Royal Free Hospital, London (V Van Someren, S McKenna); Lewisham Hospital, London (J Stroobant); Royal Hospital for Children, Bristol (A Foot).


Pediatric Pulmonary and Cardiovascular Complications of HIV Infection Study

NATIONAL HEART, LUNG AND BLOOD INSTITUTE: Hannah Peavy (Project Officer), Anthony Kalica, Elaine Sloand, George Sopko, Margaret Wu. CHAIRMAN, THE STEERING COMMITTEE: Robert Mellins. CLINICAL CENTERS: Baylor College of Medicine, Houston TX (William Shearer*, J. Timothy Bricker, Peter Hiatt, Claire Langston, Linda Davis, Teresa Tonsberg), Children's Hospital/Harvard Medical School, Boston MA (Steven Lipshultz*, Steven Colan, Andrew Colin, Kenneth McIntosh, Suzanne Steinbach, Mary Ellen Wohl, Janice Hunter), Mount Sinai School of Medicine, New York NY (Meyer Kattan*, Wyman Lai, Stephen Heaton, David Hodes, Diane Carp, Mary Anne Worth), Presbyterian Hospital in the City of New York/Columbia University, New York NY (Robert Mellins, Anastossos Koumbourlis, Jane Pitt, Thomas Starc, Kimberly Geromanos), U.C.L.A. School of Medicine, Los Angeles CA (Samuel Kaplan*, Andrea Kovacs, Arnold Platzker, Helene Cohen, Lynn Fukushima, Toni Ziolkowski). CLINICAL COORDINATING CENTER, The Cleveland Clinic Foundation, Cleveland OH: Kirk Easley*, Michael Kutner*, Mark Schluchter*, Richard Martin (Case Western Reserve University), Johanna Goldfarb, Douglas Moodie, Cindy Chen, Kirk Easley, Victoria Konig, Sunil Rao, Amrik Shah, Susan Sunkle. POLICY, DATA AND SAFETY MONITORING BOARD: Henrique Rigatto, (Chairman), Edward B. Clark, Robert B. Cotton, Vijay V. Joshi, Paul S. Levy, Norman S. Talner, Patricia Taylor, Robert Tepper, Janet Wittes, Robert H. Yolken, Peter E. Vink.
* Principal Investigator


Swiss Mother and Child HIV Cohort Study

C. Aebi, M. Battegay, E. Bernasconi, K. Biedermann, H. Bucher, Ph. Bürgisser, J.-J. Cheseaux, G. Drack, M. Egger, P. Erb, W. Fierz, M. Fischer, M. Flepp (Chairman of the SHCS Clinical and Laboratory Committee), P. Francioli (President of the SHCS, Centre Hospitalier Universitaire Vaudois, CH-1011- Lausanne), H.J. Furrer, M. Gorgievski, H. Günthard, P. Grob, T. Gyr, B. Hirschel, I. Hösli, O. Irion, L. Kaiser, K. Keller, C. Kind (Chairman of the MoCHiV Scientific Board subcommittee), Th. Klimkait, U. Lauper (Chairman of the MoCHiV Clinical and Laboratory Subcommittee), B. Ledergerber, D. Nadal, M. Opravil, F. Paccaud, G. Pantaleo, L. Perrin, J.-C. Piffaretti, M. Rickenbach, C. Rudin (Chairman of the MoChiV Substudy, Basel UKBB, Römergasse 8, CH-4058 Basel), A. Schreyer, J. Schupbach, R. Speck, A. Telenti, A. Trkola, P. Vernazza (Chairman of the SHCS Scientific Board), Th. Wagels, R. Weber, A. Wechsler, D. Wunder, C.-A. Wyler, S. Yerly.


Women and Infants Transmission Study

Principal investigators, study coordinators, program officers and funding include: Clemente Diaz, Edna Pacheco-Acosta (University of Puerto Rico, San Juan, PR; U01 AI 34858); Ruth Tuomala, Ellen Cooper, Donna Mesthene (Boston/Worcester Site, Boston, MA; 9U01 DA 15054); Jane Pitt, Alice Higgins (Columbia Presbyterian Hospital, New York, NY; U01 DA 15053); Sheldon Landesman, Edward Handelsman, Gail Moroso (State University of New York, Brooklyn, NY; U01 HD 36117); Kenneth Rich, Delmyra Turpin (University of Illinois at Chicago, Chicago, IL; U01 AI 34841); William Shearer, Susan Pacheco, Norma Cooper (Baylor College of Medicine, Houston, TX; U01 HD 41983); Joana Rosario (National Institute of Allergy and Infectious Diseases, Bethesda, MD); Robert Nugent, (National Institute of Child Health and Human Development, Bethesda, MD); Vincent Smeriglio, Katherine Davenny (National Institute on Drug Abuse, Bethesda, MD); and Bruce Thompson, Yvonne Matthews (Clinical Trials & Surveys Corp., Baltimore, MD, N01 AI 85339). Scientific Leadership Core: Kenneth Rich (PI), Delmyra Turpin (Study Coordinator) (1 U01 AI 50274-01). Additional support has been provided by local Clinical Research Centers as follows: Baylor College of Medicine, Houston,TX; NIH GCRC RR00188; Columbia University, New York, NY; NIH GCRC RR00645.