COVID-19 Update

Our primary concern is the safety of all our study participants and minimising any additional strain on our clinical sites and staff.

The COVID-19 pandemic is affecting people and health services around the world. Our primary concern is the safety of all our study participants and minimising any additional strain on our clinical sites and staff. We are working closely with our clinical sites and partner organisations to find ways of doing this. Please contact the relevant trial team via the trial email address if you have questions about what this means for a specific study.

We are working on developing several studies looking at COVID-19, including the ACTT- EU/UK trial. We hope to open this study in April 2020. It will test drugs to treat people in hospital due to the virus. The adaptive design will allow us to add new treatment comparisons as new potential ways to treat the disease are discovered.

Latest News and Updates

European Medicines Agency approves use of Dolutegravir 5 mg dispersible tablet for younger children living with HIV

These small tablets can now be used in combination with other medicines for treating children living with HIV who are aged at least four weeks and weigh at least 3kg.

19 Nov

NHS England commissions radiotherapy for men with low volume metastatic prostate cancer

This decision was made following a recommendation from the Clinical Priorities Advisory Group based on evidence from the STAMPEDE trial.

19 Nov

Shorter treatments are safe and effective for children with minimal tuberculosis

SHINE found that the four month treatment was as good as the standard six month treatment for children with minimal TB.

26 Oct

Active surveillance after surgery still best approach for kidney cancer

Results from the SORCE trial confirm that the drug sorafenib should not be used as treatment straight after surgery for kidney cancer. These results were published yesterday in the Journal of Clinical Oncology.

15 Oct

Our Research Themes

Cancer

Innovative clinical trial design and meta-analysis extending beyond the boundaries of single cancer types

Infections

Major international clinical trials answering questions of global public health significance

Methodology

Development of methods with direct impact on the design, conduct and analysis of studies

Other Research & Policy

This section will capture projects outside the current QQR themes

Our Latest Tweets

MRC CTU at UCL MRCCTU

#Publication - What factors indicate prognosis for adults with depression in primary care? A protocol for meta-analyses of individual patient data using the Dep-GP database. Read here for free 🔓: https://t.co/hUdQOmE5TS #metaanalysis #IPD

Nov 27
MRC CTU at UCL MRCCTU

#Publication - Effect of Variable Selection Strategy on the Performance of Prognostic Models When Using Multiple Imputation. Read here for free 🔓: https://t.co/2mZfjAmWa7 #StatsTwitter

Nov 26
MRC CTU at UCL MRCCTU

#Publication - 2019 update of the European AIDS Clinical Society Guidelines for treatment of people living with HIV version 10.0. Read here for free 🔓: https://t.co/Xtb34LNM1C #HIV https://t.co/3Q68Sfoetl

Nov 25