The MRC Clinical Trials Unit (CTU) is a centre of excellence for clinical trials, meta-analyses and epidemiological studies.
We are committed to strengthening and expanding the evidence base for healthcare nationally and internationally.
The CTU also develops methodology to improve the design, conduct and analysis of clinical studies, and hosts one of the MRC’s eight regional Hubs for Trials Methodology Research.
The MRC CTU is a UKCRC registered trials unit.
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Detailed analysis of data from the FEAST trial has revealed that the higher rates of death among children given rapid fluid resuscitation seem to be because of cardiovascular collapse rather than fluid overload. Fluid resuscitation increased death rates in all subgroups (the symptoms the children had, whether or not they had anaemia, and which definition of shock was used). These results question the speed & volume of fluids used for treating children in shock due to infections in Africa.
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Economic analysis of data from the DART trial, published in PLoS ONE, shows that there is little justification for the routine use of laboratory tests to monitor patients on antiretroviral therapy in Africa. In high-income countries expensive laboratory tests are used routinely. But laboratory facilities, and the money to pay for them, are both scarce in Africa.
MRC CTU is now on Twitter! We are using it to highlight news about our studies, publications and job vacancies. You can see our tweets so far (and follow us) using this link: https://twitter.com/#!/MRCCTU
Results of a survey from the MRC Clinical Trials Unit, published in the journal Trials, show that researchers think involving consumers has benefits in clinical research. Consumer involvement is the active involvement of patients, carers, members of support groups or charities or other members of the public in the design and conduct of clinical research.
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