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UKCRC Registered Clinical Trials Unit

The MRC Clinical Trials Unit (MRC CTU) at UCL is at the forefront of resolving internationally important questions in infectious diseases and cancer, and delivering swifter and more effective translation of scientific research into patient benefits.  It does this by carrying out challenging and innovative studies, and developing and implementing methodological advances in study design, conduct and analysis.  It hosts one of the MRC’s five regional Hubs for Trials Methodology Research.

The MRC CTU at UCL is a UKCRC registered trials unit and is part of the Institute for Clinical Trials and Methodology at UCL.


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Series of short films about clinical trials

Clinical trials are essential to finding out whether new healthcare interventions (such as new drugs) work. We have produced a series of short films, exploring:

  • What are randomised controlled trials and why are they important?
  • What is the MRC Clinical Trials Unit, and what does it do?
  • Where do ideas for trials come from?

and much more...

Major study into clinical trial oversight processes finds commonly used 'triggered monitoring' processes may not be effective
The results of the TEMPER study, a major MRC CTU at UCL study about how best to run clinical trials, have been published in Clinical Trials journal. They show that a commonly used approach in oversight of clinical trials, so called "triggered monitoring", may not be as effective in current practice as expected, but they also provide evidence about how the approach could be optimised and improved.

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