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Publications Conference presentations UK CHIC presentation
| Publications Back to top | |||
| 2011 |
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| Outcomes in the first year after initiation
of first-line HAART among heterosexual men and women in the
UK CHIC Study. Barber TJ, Geretti AM, Anderson J, Schwenk A, Phillips AN, Bansi L, Gilson R, Hill T, Walsh J, Fisher M, Johnson M, Post F, Easterbrook P, Gazzard B, Palfreeman A, Orkin C, Leen C, Gompels M, Dunn D, Delpech V, Pillay D, Sabin CA; UK CHIC Study Steering Committee. Antivir Ther 2011; 16:805-14. PubMed link |
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| Treatment switches during pregnancy
among HIV-positive women on antiretroviral therapy at conception. Huntington SE, Bansi LK, Thorne C, Anderson J, Newell ML, Taylor GP, Pillay D, Hill T, Tookey PA, Sabin C; on behalf of the UK Collaborative HIV Cohort (UK CHIC) Study and the National Study of HIV in Pregnancy and Childhood (NSHPC). AIDS 2011; 25:1647-55. PubMed link |
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| Long-term trends in CD4 cell counts
and impact of viral failure in individuals starting antiretroviral
therapy: UK Collaborative HIV cohort (CHIC) Study. Hughes R, Sterne J, Walsh J, Bansi L, Gilson R, Orkin C, Hill T, Ainsworth J, Anderson J, Gompels M, Dunn D, Johnson M, Phillips A, Pillay D, Leen C, Easterbrook P, Gazard B, Fisher M, Sabin C. HIV Med 2011; Epub ahead of print |
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| Responders to highly active antiretroviral
therapy and clinical events in patients with a low CD4 cell
count: late presenters vs. late starters. Waters L, Fisher M, Anderson J, Wood C, Delpech V, Hill T, Walsh J, Orkin C, Bansi L, Gompels M, Phillips A, Johnson M, Gilson R, Easterbrook P, Leen C, Porter K, Gazzard B, Sabin C; for the UK CHIC Steering Committee. HIV Med 2011; 12:289-298. PubMed link |
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| The impact of HIV drug resistance testing
on changes to treatment. Bansi L, Smith C, Phillips A, Kirk S, Geretti AM, Johnson M, Mackie N, Post F, Gazzard B, Dunn D, Sabin C; UK Collaborative HIV Cohort (CHIC) Study and the UK Collaborative Group on HIV Drug Resistance (HDRD). AIDS 2011; 25:603-10. PubMed link |
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| HIV-associated central nervous system
diseases in the recent combination antiretroviral therapy
era. UK Collaborative HIV cohort (CHIC) Study Steering Committee, Garvey L, Winston A, Walsh J, Post F, Porter K, Gazzard B, Fisher M, Leen C, Pillay D, Hill T, Johnson M, Gilson R, Anderson J, Easterbrook P, Bansi L, Orkin C, Ainsworth J, Phillips AN, Sabin CA. Eur J Neurol 2011; 18:527-34. PubMed link |
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| Antiretroviral therapy CNS penetration and HIV-1 associated CNS disease. Garvey L, Winston A, Walsh J, Post F, Porter K, Gazzard B, Fisher M, Leen, C, Pillay D, Hill T, Johnson M, Gilson R, Anderson J, Easterbrook P, Bansi L, Orkin C , Ainsworth J, Palfreeman A, Gompels M, Phillips AN, Sabin CA; UK Collaborative HIV Cohort (CHIC) study. Neurology 2011; 76:693-700. PubMed link |
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| 2010 |
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| Trends over calendar time in antiretroviral
treatment success and failure in HIV clinic populations. Bansi L, Sabin C, Delpech V, Hill T, Fisher M, Walsh J, Chadborn T, Easterbrook P, Gilson R, Johnson M, Porter K, Anderson J, Gompels M, Leen C, Ainsworth J, Orkin C, Nelson M, Rice B, Phillips A; UK Collaborative HIV Cohort (CHIC) Study and the Health Protection Agency. HIV Med 2010; 11:432-8. PubMed link |
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| The prevalence of hepatitis C virus
(HCV) infection in HIV-positive individuals in the UK -
trends in HCV testing and the impact of HCV on HIV treatment
outcomes. Turner J, Bansi L, Gilson R, Gazzard B, Walsh J, Pillay D, Orkin C, Phillips A, Easterbrook P, Johnson M, Porter K, Schwenk A, Hill T, Leen C, Anderson J, Fisher M, Sabin C; UK Collaborative HIV Cohort (UK CHIC) Study. J Viral Hepat 2010; 17:569-77. PubMed link |
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| The effect of transmitted HIV-1 drug
resistance on pre-therapy viral load. Harrison L, Castro H, Cane P, Pillay D, Booth C, Phillips A, Geretti AM, Dunn D; UK Collaborative Group on HIV Drug Resistance and the UK Collaborative HIV Cohort Study (UK CHIC). AIDS 2010; 24:1917-22. PubMed link |
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| Long-term probability of detecting
drug-resistant HIV in treatment-naive patients initiating
combination antiretroviral therapy. UK Collaborative Group on HIV Drug Resistance; UK CHIC Study Group. Clin Infect Dis 2010; 50:1275-85. PubMed link |
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| Impact of transmitted drug-resistance
on treatment selection and outcome of first-line Highly Active
Antiretroviral Therapy (HAART). Bansi L, Geretti AM, Dunn D, Hill T, Green H, Fearnhill E, Gazzard B, Nelson M, Porter K, Phillips A, Sabin C; UK Collaborative Group on HIV Drug Resistance and UK Collaborative HIV Cohort (CHIC) Study. J Acquir Immune Defic Syndr 2010; 53:633-9. PubMed link |
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| Late diagnosis in the HAART era: proposed
common definitions and associations with mortality. UK Collaborative HIV Cohort (UK CHIC) Steering committee, Sabin CA, Schwenk A, Johnson MA, Gazzard B, Fisher M, Walsh J, Orkin C, Hill T, Gilson R, Porter K, Easterbrook P, Delpech V, Bansi L, Leen C, Gompels M, Anderson J, Phillips AN. AIDS 2010; 24:723-7. PubMed link |
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| Discordant responses on starting highly
active antiretroviral therapy: suboptimal CD4 increases despite
early viral suppression in the UK Collaborative HIV Cohort
Study (UK CHIC). Gilson R, Man S-L, Copas A, Rider A, Forsyth S, Hill T, Bansi L, Porter K, Gazzard B, Orkin C, Pillay D, Schwenk A, Johnson M, Easterbrook P, Walsh J, Fisher M, Anderson J, Leen C, Sabin CA; UK Collaborative HIV Cohort Study Group. HIV Med 2010; 11:152-60. PubMed link |
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| Factors influencing lopinavir and atazanavir
plasma concentration. Stöhr W, Back D, Dunn D, Sabin C, Wilson A, Gilson R, Pillay D, Hill T, Ainsworth J, Gazzard B, Leen C, Bansi L, Fisher M, Orkin C, Anderson J, Johnson M, Easterbrook P, Gibbons S, Khoo S, UK CHIC Steering Committee. J Antimicrob Chemother 2010; 65:129-37. Pubmed link |
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| 2009 |
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| Clinical epidemiology of HIV-associated
end-stage renal failure in the UK. Bansi L, Hughes A, Bhagani S, Mackie NE, Leen C, Levy J, Edwards S, Connolly J, Holt SG, Hendry BM, Sabin C, Post FA; UK CHIC/ESRF study group. AIDS 2009; 23:2517-21. PubMed link |
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Factors influencing efavirenz and
nevirapine plasma concentration: effect of ethnicity, weight
and co-medication. |
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| The associations between age and the
development of laboratory abnormalities and treatment discontinuation
for reasons other than virological failure in the first year
of highly active antiretroviral therapy. Sabin CA Smith CS, Delpech V, Anderson J, Bansi L, Gilson R, Schwenk A, Leen C, Gazzard B, Porter K, Mackie N, Fisher M, Orkin C, Johnson M, Easterbrook P, Hill T, Phillips AN; UK Collaborative HIV Cohort (CHIC) Study. HIV Med 2009; 10:35-43. PubMed link |
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| CD4 counts and the risk of systemic
non-Hodgkin's lymphoma in individuals with HIV in the UK. Bower M, Fisher M, Hill T, Reeves I, Walsh J, Orkin C, Phillips AN, Bansi L, Gilson R, Easterbrook P, Johnson M, Gazzard B, Leen C, Pillay D, Schwenk A, Anderson J, Porter K, Gompels M, Sabin CA; UK CHIC Steering Committee. Haematologica 2009; 94:875-80. PubMed link |
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| Is 1 alanine transaminase >200 IU
enough to define an alanine transaminase flare in HIV-infected
populations? A new definition derived from a large cohort
study. Bansi L, Turner J, Gilson R, Post F, Gazzard B, Leen C, Anderson J, Porter K, Hill T, Fisher M, Ainsworth J, Pillay D, Johnson M, Wilson A, Orkin C, Easterbrook P, Phillips A, Sabin C; on behalf of the UK Collaborative HIV Cohort (CHIC) Study. J Acquir Immune Defic Syndr 2009 Epub ahead of print PubMed link |
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| 2008 |
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| Treatment switches after viral rebound
in HIV-infected adults starting antiretroviral therapy: multicentre
cohort study. United Kingdom Collaborative HIV Cohort Study, Lee KJ, Dunn D, Gilson R, Porter K, Bansi L, Hill T, Phillips AN, Sabin CA, Schwenk A, Leen C, Delpech V, Anderson J, Gazzard B, Johnson M, Easterbrook P, Walsh J, Fisher M, Orkin C. AIDS 2008; 22:1943-50. PubMed link |
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| Patterns and predictors of the use
of different antiretroviral drug regimes at treatment initiation
in the UK. Easterbrook PJ, Phillips AN, Hill T, Matthias R, Fisher M, Gazzard B, Gilson R, Scullard G, Johnson M, Dunn DT, Orkin C, Anderson J, Schwenk A, Leen C, and Sabin CA; on behalf of the UK Collaborative HIV Cohort (CHIC) Study Steering Committee. HIV Medicine 2008; 9:47-56. PubMed link |
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| Are prior treatment interruptions associated
with higher viral rebound rates in patients with viral suppression? Bansi LK, Benzie AA, Phillips AN, Portsmouth S, Hill T, Leen C, Schwenk A, Johnson M, Anderson J, Gilson R, Easterbrook P, Gazzard B, Fisher M, Orkin C, Porter K, Pillay D, Taylor GP, Walsh JC, Sabin CA; UK Collaborative HIV Cohort (UK CHIC) Study. AIDS 2008; 22:349-56. PubMed link |
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| Changes in outcome of persons initiating
HAART at CD4 less than 50 cells/mm3. K Porter, S Walker, T Hill, J Anderson, C Leen, M Johnson, B Gazzard, J Walsh, M Fisher, C Orkin, A Schwenk, R Gilson, P Easterbrook, V Delpech, CA Sabin; on behalf of the UK CHIC Study Group. J Aquir Immune Defic Syndr 2008; 47:202-205. PubMed link |
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| 2007 |
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Risk of extensive virologic failure
to the three original antiretroviral drug classes over
long term follow-up from the start of therapy among patients
with HIV infection: an observational cohort study. |
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| HIV diagnosis at CD4 count above 500/mm3
and progression to below 350/mm3 without antiretroviral therapy. UK Collaborative HIV Cohort (CHIC) Study Steering Committee. J Acquir Immune Defic Syndr 2007; 46:275-8. PubMed link |
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| Rate of AIDS diseases or death in HIV-infected
antiretroviral therapy-naive individuals with high CD4 cell
count. The UK Collaborative HIV Cohort (CHIC) Study Steering Committee. (Analysis and writing committee/UK CHIC steering committee: Phillips AN, Gazzard B, Gilson R, Easterbrook P, Johnson M, Walsh J, Leen C, Fisher M, Orkin C, Anderson J, Pillay D, Delpech V, Sabin C, Schwenk A, Dunn D, Gompels M, Hill T, Porter K, Babiker A; UK Collaborative HIV Cohort Study.) AIDS 2007; 21:1717-1721. PubMed link |
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| Increased duration of viral suppression
is associated with lower viral rebound rates in patients
with previous treatment failures. Benzie AA, Bansi LK, Sabin CA, Portsmouth S, Hill T, Johnson M, Gilson R, Easterbrook P, Gazzard B, Fisher M, Orkin C, Dunn D, Delpech V, Taylor GP, Walsh JC, Phillips AN on behalf of the UK Collaborative HIV Cohort (CHIC) Study. AIDS 2007; 21:1423-1430. PubMed link |
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| CD4 cell count and initiation of antiretroviral
therapy: trends in seven UK centres, 1997-2003. Stöhr W, Dunn DT, Porter K, Hill T, Gazzard B, Walsh J, Gilson R, Easterbrook P, Fisher M, Johnson MA, Delpech VC, Phillips AN and Sabin CA, on behalf of the UK CHIC Study. HIV Medicine 2007; 8(3): 135-141. PubMed link |
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| 2005 |
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| The rate of viral rebound after attainment
of an HIV load <50 copies/mL according to specific antiretroviral
drugs in use: Results from a multicenter cohort study. Smith CJ, Phillips AN, Hill T, Fisher M, Gazzard B, Porter K, Gilson R, Easterbrook P, Scullard G, Matthias R, Johnson MA, Sabin CA; United Kingdom Collaborative HIV Cohort Study Group. J Infect Dis. 2005 Oct;192(8):1387-97 PubMed link |
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| Treatment exhaustion of highly active
antiretroviral therapy (HAART) among individuals infected
with HIV in the United Kingdom: multicentre cohort study. Sabin CA, Hill T, Lampe F, Matthias R, Bhagani S, Gilson R, Youle MS, Johnson MA, Fisher M, Scullard G, Easterbrook P, Gazzard B, Phillips AN; UK Collaborative HIV Cohort (UK CHIC) Study Group. BML 2005 Mar 330(7493):695 PubMed link |
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| 2004 |
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| The creation of a large UK-based multicentre
cohort of HIV-infected individuals: The UK Collaborative
HIV Cohort (UK CHIC) Study. The UK Collaborative HIV Cohort Steering Committee. HIV Med. 2004 Mar;5(2):115-24 PubMed link |
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| Conference Presentations Back to top | |||
| 2009 |
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| Improving the quality of death data
in the UK CHIC Study. T Hill, T Hartney, T Chadborn, V Delpech and C Sabin. 15th Annual Conference of the British HIV Association, 2009. Abstract/Poster P109. |
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| Factors influencing lopinavir (LPV)
and atazanavir (ATV) plasma concentration. W Stöhr, S Khoo, D Dunn, S Gibbons, T Hill, A Winston, C Sabin, D Back. 15th Annual Conference of the British HIV Association, 2009. Abstract/Poster 135. |
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| Clinical epidemiology of end-stage
renal failure in the UK. A Hughes, L Bansi, J Connolly, S Edwards, N Mackie, M Fisher, C Sabin and F Post. 15th Annual Conference of the British HIV Association, 2009. Abstract/Oral O5. |
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| Linkage of the UK Collaborative HIV
cohort (CHIC) study and the National Study of HIV in Pregnancy
and Childhood (NSHPC) to assess ART patterns in pregnant
women. L Bansi, C Thorne, P Tookey and C Sabin. 15th Annual Conference of the British HIV Association, 2009. Abstract/Poster P56. |
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| Late diagnosis in the HAART era: what
do we mean by a late presenter? C Sabin on behalf of the UK CHIC Study. 13th International Workshop on HIV Observational Databases, 2009. Abstract/Oral 1. |
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| Trends over calendar time in antiretroviarl
treatment success and failure in HIV clinic populations. L Bansi, C Sabin, V Delpech, A Phillips onn behalf of the UK CHIC Study. 13th International Workshop on HIV Observational Databases, 2009. Abstract/Oral 26. |
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| 2008 |
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| Viral rebound according to specific
antiretrovirals in people who attain a viral load of less
than 50 copies/ml. C Smith, A Phillips, M Fisher for the UK Collaborative HIV Cohort (UK CHIC). 9th International Congress on Drug Therapy in HIV Infection, 2008. Abstract/Poster 604. |
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| Do the disadvantages of late presentation
of HAART persist in patients achieving and maintaining viral
load (VL) suppression for a year on HAART? LJ Waters, M Fisher, J Anderson, C Wood and CA Sabin. 9th International Congress on Drug Therapy in HIV Infection, 2008. Abstract/Oral O422. |
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| Trends in transmitted HIV drug resistance
among non-B subtypes in the UK. D Chilton, L Harrison, H Green, S Lattimore, V Delpech, D Pillay. 9th International Congress on Drug Therapy in HIV Infection, 2008. Abstract/Oral O112. |
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| The frequency and clinical implications
of a discordant CD4 count and CD4 percentage. M Gompels, C Sabin, A Phillips, D Dunn and the UK Collaborative HIV Cohort (CHIC) Study. 15th Conference on Retroviruses and Opportunistic Infections, 2008. Abstract 343. |
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| Cumulative risk of extensive triple-class
virologic failure in 10,603 patients followed as long as
10 years from the start of ART. A Phillips, A Wilson, C Leen, and the UK CHIC Study Group. 15th Conference on Retroviruses and Opportunistic Infections, 2008. Abstract 532. |
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| Factors influencing efavirenz (EFV)
and nevirapine (NVP) plasma concentration. W Stöhr, S Khoo, D Dunn, S Gibbons, T Hill, A Winston, C Sabin, D Back. 14th Annual Conference of the British HIV Association, 2008. Abstract/Poster P145. |
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| Association between adverse events
and mortlity: a validation analysis. C Sabin, L Bansi, M Nelson, C Leen, UK CHIC Steering Committee. 14th Annual Conference of the British HIV Association, 2008. Abstract/Oral O12. |
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| Responses to HAART and clinical events
in patients with a low CD4 count: late presenters versus
late starters. LJ Waters, MJ Fisher, J Anderson, C Wood, C Sabin for the UK CHIC Study Group. 14th Annual Conference of the British HIV Association, 2008. Abstract/Oral O30. |
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| Implications of post-HAART virological
failure for trends in CD4 count - UK CHIC Study. R Hughes, C Sabin, JAC Sterne. 12th International Workshop on HIV Observational Databases, 2008. Abstract/Poster 58. |
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| Factors influencing efavirenz and nevirapine
plasma concentration. W Stöhr, S Khoo, D Dunn, S Gibbons, T Hill, A Winston, C Sabin, D Back on behalf of the Liverpool TDM Database and the UK CHIC Study. 12th International Workshop on HIV Observational Databases, 2008. Abstract/Oral 27. |
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| Does the CD4 percentage provide additional
prognostic information to the absolute CD4 count in the highly
active antiretroviral therapy (HAART) era? CA Sabin, DT Dunn, AN Phillips, M Gompels. 12th International Workshop on HIV Observational Databases, 2008. Abstract/Oral 20. |
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| Is one ALT >200 enough to be defined
as an ALT flare: Differentiating between elevations and ALT
flares. L Bansi, J Turner, R Gilson, C Sabin. 12th International Workshop on HIV Observational Databases, 2008. Abstract/Oral 28. |
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| 2007 |
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| Association between resistance and
CD4 count change in patients on ART with ongoing viraemia. ZV Fox, AN Phillips for the UK Resistance Database, EuroSIDA and UK CHIC Studies. 11th International Workshop on HIV Observational Databases, 2007. Abstract/Poster 95. . |
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| Reducing the impact of loss-to-follow-up
in observational cohort studies. L Bansi, T Hill, CA Sabin. 11th International Workshop on HIV Observational Databases, 2007. Abstract/Poster 66. |
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| Comparison of age/sex-specific all
cause death rates in ART-naive patients with CD4 count >350
cells/mm3 compared with the general population: proposal
for a joint analysis. R Lodwick, AN Phillips for the UK CHIC Study. 11th International Workshop on HIV Observational databases, 2007. Abstract/Oral 20. |
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| Identifying toxicity-related treatment
discontinuations (TRTD) in the absence of complete data on
reasons for discontinuation. CA Sabin, C Smith, AN Phillips, for the UK CHIC Study. 11th International Workshop on HIV Observational Databases, 2007. Abstract/Oral 16. |
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| Time trends in HIV drug resistnce in
ART-experienced patients in the UK: impact of improved treatments
and boosted protease inhibitors. D Dunn, H Green, E Fearhill. 13th Annual Conference of the British HIV Association, 2007. Abstract/Oral O2 Ref: HIV Medicine, 8 (Suppl.1), 1-8. |
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TB incidence among HIV-infected
africans in the United Kingdom.
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Long-term trends in CD4 counts in
patients starting HAART: UK CHIC study.
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| Antiretroviral changes after viral
load rebound in the UK Collaborative HIV Cohort (CHIC) study. KJ Lee, DT Dunn, CA Sabin for the UK CHIC Study steering committee. 11th European AIDS Conference/EACS, 2007. Presentation |
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| Trends over calendar time in the prevalence
of patients with extensive triple class virologic failure
in the UK. A Phillips, A Wilson, C Leen on behalf of UK CHIC. 13th Annual Conference of the British HIV Association, 2007. Presentation |
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| 2006 |
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| HCV co-infection in the UK Collaborative
HIV Cohort (UK CHIC) Study. J Turner, L Bansi, RC Gilson, CA Sabin. 12th Annual Conference of the British HIV Association, 2006. Presentation |
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| 2005 |
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| Immunological and clinical consequences
of sustained low-level viremia in patients receiving HAART. T Welz, L Bansi, P Easterbrook, C Sabin on behalf of the UK Collaborative HIV Cohort Study (CHIC). 3rd IAS Conference on HIV Pathogenesis and Treatment, 2005. Presentation |
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