The MRC Clinical Trials Unit (CTU) is a centre of excellence for clinical trials, meta-analyses and epidemiological studies

We are committed to strengthening and expanding the evidence base for healthcare nationally and internationally.

The CTU also develops methodology to improve the design, conduct and analysis of clinical studies, and hosts one of the MRC’s eight regional Hubs for Trials Methodology Research.

The MRC CTU is a UKCRC registered trials unit.

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Latest News

Results of CHAPAS-3 trial on which drugs to use for children with HIV in Africa

The results of the CHAPAS-3 trial were presented by Victor Musiime at the 6th International Workshop on HIV Pediatrics in Melbourne on 19 July. CHAPAS-3 looked into the safety and effectiveness of three different drugs used as part of a combination to treat children with HIV in Africa. One of the main findings from the trial was that children respond very well to HIV treatment, regardless of which specific treatment they receive.

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EARNEST trial results support World Health Organisation guidelines for second-line treatment of HIV

The results of the EARNEST trial, published today in the New England Journal of Medicine, provide support for the current World Health Organisation (WHO) guidelines for treating people with HIV whose initial treatment is no longer working.

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The STAMPEDE (MRC PR08) trial: update on recent data and future plans

The STAMPEDE Trial Management group has been reflecting on recent publications and presentations at ASCO 2014 of randomised controlled trials assessing zoledronic acid or docetaxel for hormone-naïve prostate cancer. The STAMPEDE Trial Management Group has issued a statement.

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