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At the MRC Clinical Trials Unit, systematic reviews and meta-analyses are a core part of our work.  We are committed to a rigorous, evidence-based approach to planning trials. 

This planning includes the need to decide whether a systematic review or new trial offers the best means of addressing specific questions.

The Meta-analysis Group research programme includes systematic reviews and meta-analysis based on both individual patient data (IPD) and summary data, as well as associated methodological research. 

The Meta-analysis Group also provides the main link between the MRC Clinical Trials Unit and the Cochrane Collaboration.

Most of the Group’s work to date has been in the cancer field, but our remit has extended to other diseases and conditions with projects in Prion disease, pregnancy and wound care.

Future work will focus on key questions in cancer and in a range of healthcare fields.

Further information